Risperdal Risperidone: Side Effects, Uses, Dosage, Interactions, Warnings

The first dose of Rykindo should be administered 4 to 5 weeks after the last dose of Risperdal Consta. Risperidone may help control your symptoms but will not cure your condition. It may take several weeks or longer before you feel the full benefit of risperidone. Do not stop taking risperidone without talking to your doctor. If you suddenly stop taking risperidone, your symptoms may return and your illness may become harder to treat.

The effect appeared to be in females, since impaired mating behavior was not noted in the male fertility study. In a subchronic study in Beagle dogs in which risperidone was administered orally at doses of 0.31 to 5 mg/kg, sperm motility and concentration were decreased at doses 0.6 to 10 times the MRHD based on mg/m² body surface area. Dose-related decreases were also noted in serum testosterone at the same doses. Serum testosterone and sperm parameters partially recovered, but remained decreased after treatment was discontinued. A no-effect dose could not be determined in either rat or dog.

• In a subchronic study in Beagle dogs in which risperidone was administered orally at doses of 0.31 to 5 mg/kg, sperm motility and concentration were decreased at doses 0.6 to 10 times the MRHD based on mg/m² body surface area.
• Some female patients receiving this medicine have become infertile (unable to have children).
• The effective dose range is 1 mg to 6 mg per day, as studied in the short-term, placebo-controlled trials.
• Be careful if you drive or do anything that requires you to be alert.

Pregnancy

• Avoid driving or hazardous activity until you know how risperidone will affect you.
• In general, the most frequently reported signs and symptoms are those resulting from an exaggeration of the drug’s known pharmacological effects, i.e., drowsiness, sedation, tachycardia, hypotension, and extrapyramidal symptoms.
• This includes prescription or nonprescription (over-the-counter OTC) medicines and herbal or vitamin supplements.
• Risperdal (0.25 mgtwice daily) did not show a clinically relevant effect on the pharmacokineticsof digoxin.
• Inform patients with Phenylketonuria and caregivers that RISPERDAL M-TAB Orally Disintegrating Tablets contain phenylalanine.
• Uzedy belongs to a group of medicines called second-generation (atypical) antipsychotics.

Using alcohol or tobacco with certain medicines may also cause interactions to occur. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. You should avoid drinking alcohol while using risperidone.

Medications & Supplements

Antipsychotic medications can be used to treat several kinds of mental health conditions. Low Blood Pressure Upon Standing (Orthostatic Hypotension) and Falls. Uzedy may cause a sudden drop in blood pressure when standing up from a seated or lying position. To help prevent this, be careful not to get up too quickly. If you feel dizzy, sit or lie down right away until the dizziness stops, then take your time getting up again.

Related treatment guides

Tell your doctor all medications and supplements you use. Tell your doctor if you experience serious side effects of Risperdal including difficulty swallowing, muscle spasms, shaking (tremor), mental/mood changes, or signs of infection (such as fever, persistent sore throat). If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or go to the nearest emergency room. Risperidone oral tablet can interact with other medications, vitamins, or herbs you may be taking. When switching from Risperdal Consta IM ER to Rykindo IM ER, administer the exact dosage.

Talk to your care team about the use of this medication in children. While this medication may be prescribed for children as young as 5 years of age for selected conditions, precautions do apply. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

Does Uzedy interact with other medicines (drug interactions)?

Pooled data from 3 placebo-controlled, 3- to 6-week, fixed-dose studies in children and adolescents with schizophrenia (13-17 years of age), bipolar mania (10-17 years of age), or autistic disorder (5-17 years of age) are presented in Table 5. Older adults with dementia may also have a greater chance of having a stroke or ministroke during treatment. These are signs that your use of this drug is causing a negative reaction in your body that will require additional treatment. Signs of an allergic reaction include hives, difficulty breathing, rash, itchiness or swelling. This medication is used to treat the symptoms of bipolar disorder, schizophrenia, and in some cases Tourette syndrome and behavioral problems in those with dementia or autism.

In clinical trials in 1885 children and adolescents treated with RISPERDAL, 2 (0.1%) patients were reported to have tardive dyskinesia, which resolved on discontinuation of RISPERDAL treatment see also WARNINGS AND PRECAUTIONS. In a rat cross-fostering study the number of live offspring was decreased, the number of stillbirths increased, and the birth weight was decreased in offspring of drug-treated pregnant rats. In addition, the number of deaths increased by Day 1 among offspring of drug-treated pregnant rats, regardless of whether or not the offspring were cross-fostered. Risperidone also appeared to impair maternal behavior in that offspring body weight gain and survival (from Day 1 to 4 of lactation) were reduced in offspring born to control but reared by drug-treated dams. All of these effects occurred at 5 mg/kg which is 3 times the MRHD based on mg/m² and the only dose tested in the study. Oral administration of risperidone to pregnant mice caused cleft palate at doses 3 to 4 times the maximum recommended human dose (MRHD) with maternal toxicity observed at 4-times MRHD based on mg/m² body surface area.

Uzedy is given to you by a healthcare provider every one or two months in a hospital, clinic, or pharmacy. It is given as an injection under the skin in your upper arm or stomach area. You should have taken risperidone (the medicine in Uzedy) by mouth before starting Uzedy to make sure you tolerate the medicine.

Risperidone, Oral Tablet

Antipsychotic treatment, itself, however, may suppress (or partially suppress) the risperidone risperdal: uses, interactions and side effects signs and symptoms of the syndrome, possibly masking the underlying process. The effect that symptomatic suppression has upon the long-term course of the syndrome is unknown. Given the primary CNS effects of risperidone, caution should be used when RISPERDAL is taken in combination with other centrally acting drugs and alcohol. RISPERDAL® M-TAB® (risperidone) Orally Disintegrating Tablets are etched on one side with “R0.5”, “R1”, “R2”, “R3”, or “R4” according to their respective strengths. RISPERDAL M-TAB Orally Disintegrating Tablets 0.5 mg, 1 mg, and 2 mg are packaged in blister packs of 4 (2 X 2) tablets. Orally Disintegrating Tablets 3 mg and 4 mg are packaged in a child-resistant pouch containing a blister with 1 tablet.

Patients who develop orthostatic hypotension have a drop in their blood pressure when they rise from a lying position and may become dizzy or even lose consciousness. This educational activity covers FDA-approved indications, mechanisms of action, administration methods, adverse events, contraindications, and monitoring requirements of risperidone. The discussion focuses on evidence-based strategies to optimize the effectiveness of risperidone while reducing potential adverse effects. This program underscores the critical role of the interprofessional healthcare team in managing risperidone therapy and supporting safe and individualized treatment. Certain medications taken with risperidone may increase the risk of more severe side effects.

Seniors may be more likely to have orthostatic hypotension (a decrease in blood pressure when you stand up from a sitting or lying position) caused by this drug. Consuming alcoholic drinks while taking risperidone can increase your risk for drowsiness from risperidone. If you drink alcohol, talk with your doctor about whether risperidone is safe for you. Examples of drugs that can cause interactions with risperidone are listed below. You may be at a higher risk for falls if you’re an adult who’s over age 65 years and taking other medications that cause drowsiness.

What may interact with this medication?

RISPERDAL M-TAB Orally Disintegrating Tablets disintegrate in the mouth within seconds and can be swallowed subsequently with or without liquid. Patients should not attempt to split or to chew the tablet. RISPERDAL M-TAB Orally Disintegrating Tablets 3 mg and 4 mg are supplied in a child-resistant pouch containing a blister with 1 tablet each. This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects. Get medical help right away, if you have any of the symptoms listed above.